Abstract: With the deepening of actual combat requirements of weapon equipment, the mission profile of the weapon systems is becoming more complicated. Because of the concentration of weapon hazard sources, the risk of failures and dangerous accidents is widespread, and the safety problem is prominent. In this paper, a multi-view mission profile model was established firstly, taking process view as the core and function view, organization view, information view, resource view, and time sequence logic view as the supplementary elements to identify weapon system. Then, a formal modeling language SysML was used to build the multi-view model of the weapon mission process, and the complex mission profile of the weapon system was described from multiple perspectives. Finally, the weapon system safety analysis method was established based on the SysML view model. A land-based missile weapon system was taken as an example to study the mission profile modeling and safety analysis method based on multi-view, providing a theoretical and technical support for improving the weapon system safety analysis.