Abstract: The vibration of the centrifugal impeller and its amplitude are affected by the added mass and damping of the surrounding water. In order to clarify the influence of different submerged depths on dynamic response characteristics of the centrifugal impeller, numerical and experimental studies were carried out. The modal analysis of the impeller under air and different submerged depth conditions were carried out based on coupled acoustic fluid-structure method. The response parameter of the impeller structure in air and in different submerged depth conditions were obtained through hammering method, and then the numerical prediction accuracy of natural frequency was evaluated. Based on simulation and experimental results, the variation laws of mode shape, added mass and damping ratio with different submerged depths were constructed. The results show that the mode shape does not change as the submerged depth increases. However, the added mass and damping coefficients of the impeller increase linearly with the increase of the relative submerged depth. If the impeller is fully submerged, the added mass and hydrodynamic damping ratio are 0.39 times and 1.76 times of those in air, respectively.