Abstract: A new type of vibration isolator with amplifying mechanism was proposed by using a four-end articulated rod. Firstly, the analytical expression of the dynamic response of the vibration isolation system was obtained based on the harmonic balance method, and some parameters were got respectively, including the amplitude-frequency response, phase-frequency response, absolute displacement transmission rate, equivalent stiffness coefficient and equivalent damping coefficient of the vibration isolation system. The theoretical calculation results of the vibration isolation effect in the time domain and the frequency domain were compared with the conventional linear vibration isolator, and the verification test was carried out. Finally, the influence of system parameters on the dynamic performance of the vibration isolation system with amplification mechanism was analyzed, getting the influence mechanism. The results show that compared with the conventional linear isolators, the amplitude of the absolute displacement transfer rate of the inertial mass can be significantly attenuated by the vibration isolator with the amplification mechanism under the multi-frequency excitation in the time domain. Similarly, in the frequency domain, the amplitude of the absolute displacement transmission rate of the inertial mass can also be significantly attenuated, and the resonant frequency shifts slightly to the high frequency. The design parameters of the vibration isolation system have a great influence on the vibration isolation performance, and different vibration isolation targets can be realized by flexibly adjusting the design parameters of the vibration isolation system.