Abstract: Aiming at the terminal demolition lethality of reactive fragments, the ability of perforation, ignition and detonation for reactive fragments were investigated by experiments in this paper. The result showed that a reactive fragment weighting 2.5 g could perforate the 8 mm-thick LY12 hard aluminum under the collision velocity of 870 m/s, forming penetration holes of a diameter about 1.6~2.0 times diameter of the fragment on target plates. The reactive fragment weighting 10 g could ignite aviation kerosene in the fuel tank shell of 10 mm-thick LY12 hard aluminum at a velocity of more than 800 m/s. Furthermore, it could also detonate the warhead charge after perforating through the 6 mm-thick A3 steel plate at a velocity of more than 960 m/s. Therefore, it can be learned through the analysis of the perforation ability of reactive fragments that reactive fragments perforating a certain thickness of target plates can reliably reach its initiation threshold and ignite fuel or detonate charge.