Abstract: A friction coefficient calculation model was established for heavy pressure local contact of wet Cu-based friction pairs to study the influence of heat fade, temperature, sliding speed and contact pressure on the mixture lubrication oil film and the change rule of friction coefficient. The model was validated by the friction coefficient measuring experiments of pin-plate. The results show that, under the condition of local high pressure the variation of friction coefficient with temperature can be divided into four stages, oil film leading stage of mixed lubrication, asperity domination stage of mixed lubrication, dry friction stage and heat fade stage. Furthermore, the oil film leading stage will be vanished when the sliding speed is low. Under the dry friction condition, sliding speed has little influence on friction coefficient. However, under the mixed lubrication condition, the friction coefficient decreases with the increase of sliding velocity. When the local pressure is not very heavy, the influence on friction coefficient is very little. While the local contact pressure exceeds 100 MPa, pressure begins to affect the friction coefficient.