Abstract: To investigate fragmentation of rock and vibration of millisecond delay under multi-hole blasting, full restart method of numerical simulation and Lagrangian formula were taken to simulate the fragmentation of rock and the vibration of tunnel excavation. The vibration velocity of the characterized place in the rock was attained. The results of numerical simulations showed agreement with experiments. The results indicate that combining the full restart method of numerical simulation and Lagrangian formula could simulate the vibration and fragmentation of rock blasting.