Abstract: The basic neuron mass model was constructed,the three typical forms brain waves was simulated.The basic model was extended to multi-kinetics NMM and multi-channel coupled NMM.In the two new models,the EEG signals under different coupling strengths and different coupling direction were simulated by changing the coupling parameters of the model.The result shows that the multi-kinetics NMM can output more abundant signals by adjust the weight coefficient of the model.With the increase of coupling coefficient in multi-channel coupled NMM,low frequency component was more obvious.Low frequency single spectrum peak occurs when the coefficient threshold was reached.In this paper,EEG signal from the acupuncture stimulation was simulated;the results show that the increase of the coupling coefficient can enhance synchronization between the different channels of the signal.