Abstract: To fully analyze the random noise radiation interference on the frequency equipment, the electromagnetic effect of communication equipment under Gaussian random noise radiation was studied. Analyzing the in-band interference mechanism of power-sensitive communication equipment, a prediction model was established and the effect index was defined. The random noise radiation interference of the communication equipment was predicted by calculating the effect index. Taking the VHF radio as the experimental object, sine and AM wave, Gauss white noise, narrowband noise tests were carried out respectively. The interference probabilities under different test conditions were set as 100%, 98.7%, 99.9%, 99.1%. The test results show that the proposed model and prediction method can effectively forecast the viability of the communication equipment under the random noise radiation interference, possessing important engineering application value.