Abstract: The high order of object mode and low robustness are caused generally in the design of integrated guidance and control (IGC) due to much consideration about the rapid response, least time delay and the coupling relation between control and guide. In order to solve the problems and to achieve a high precise tracking in the zero line of sight rate reference and enhance the capability of anti-jamming, an integrated guidance and control algorithm was proposed in this paper based on integral backstepping method, introducing an incremental integral control to the system like a PI controller. High order differential of the line of sight were achieved by constructing high order sliding mode differentiator, while the convergence speed and accuracy of the observed value were ensured. In an attempt to eliminate the adverse influence on the miss distance, the immersion and invariance estimator was designed to estimate the target maneuvering information. Simulation results show that integrated guidance and control can implement a hit-to-kill and have great potential in inhibiting the adverse effects of target maneuver and improving the robustness of the system.