Abstract: The Zr/W/PTFE reactive material was sintered by hot-pressing, the microstructure photos and the quasi-static compression mechanical properties were investigated experimentally using SEM and MTS at room temperature. Results show that the density and strength of Zr/W/PTFE material will reduce when the sintering temperature is too high or too low. The quasi-static compression curves can be broadly divided into elastic deformation region,inelastic deformation region and strain softening region, and also demonstrate a distinct strain rate effect in the material. The specimens display three kinds of fracture modes, the splitting failure, the shear failure and the splitting/shear failure under the static compressive load. According to the failure strength with strain rate and visco-elastoplasticity, a modified Sargin constitutive model of the material at low strain rate was proposed. The simulation results of the constitutive model well accord with the experimental results.