Abstract: To accurately determine the parameters of the rock mass RHT constitutive model, a systematic study was conducted by integrating rock mechanics experiments, Hoek-Brown criterion modification, and numerical simulation validation. Through fundamental mechanical tests, data were obtained and key parameters were derived, leading to the determination of RHT constitutive model parameters for the marble rock mass. Using these parameters, a blast crater simulation was performed, and the results were compared with field blast crater test data, showing an average error of only 5.2%, which effectively verified the accuracy of the parameters. The parameter system was then applied to optimize blasting parameters for a blind raise. The optimal charging parameters were determined as follows: stemming lengths of 50 cm for cut holes, 80 cm for auxiliary holes, and 80 cm for perimeter holes, with an interlayer stemming length of 80 cm. Additionally, the charging parameters for adjacent cut holes between layers were optimized, and the staggered combination charging technique was thoroughly investigated. A staggered charging scheme with a height difference of 40 cm between two cut holes was proposed. Engineering results demonstrated that the optimized blasting parameters significantly improved blind raise blasting effect, increasing raise depth by 0.8 m, resolving issues such as unbroken rock at the hole bottom and under-excavation in intermediate layers. This study provides a scientific basis for one-time raise blasting design of blind raises.