Abstract: After the core technologies of Web 2.0 that promoted the operation of open innovation were introduced, the article established a multi-level network of open innovation participants of enterprises applying the theory of multi-layer innovation system, and discussed the technology source of the open innovation under the background of Web2.0. Then, four platforms of open innovation network were constructed as the core links of the three stage operation mode of open innovation based on the four core technologies of Web 2.0, namely technology resource collection and integration platform, technical scheme evaluation platform, technical scheme optimization platform, creative project experience test platform and users'communication and feedback platform. Based on all above, supporting measures to ensure the model running smoothly were put forward.