Fully-Differential Multichannel Integrated Neural Signal Recording Front-End

Neural signal can be used for clinical disease diagnosis, data analysis and real-time life signal monitoring. Its analysis requires high-performance signal processors.Based on the 180nm standard CMOS technology, a 16-channel fully-differential neural recording chip is designed. The chip consists of 16-channel low-noise pre-amplifiers, a multiplexer and a successive approximation register (SAR) ADC. The result shows that the equivalent input-referred noise of recording amplifier is 3.63 μV, bringing down noise efficiency factor to 4.24 At 8.5 bits effective number of bit (ENOB), the analog-to-digital converter (ADC) has an SNR of 52.6dB. The core area of the proposed neural recording front-end is about 2.46mm².